
The staff adjusts to the new normal of the pandemic. Dr. Choi, Dr. Lanik and April fight on the front lines. Dr. Halstead and Hannah face a troubling reality. Dr. Charles tries to clear the air with his daughter following recent developments.
Guest Stars:
Jessy Schram, Michelle Hurst, Tom Choi, Brenna DiStasio, Teddy Boone
Goodwin announces a new ED Chief and the choice doesn't make everyone happy. Dr. Manning takes a stand for her patient and finds herself dealing with the repercussions. Dr. Charles tends to family affairs.
Guest Stars:
Danielle Moné Truitt, Dominique La'Shea, Charin Alvarez, Christopher Meister, Xavier Lagunas
Dr. Charles and April team up to take on a mysterious patient in the ED. Dr. Halstead is forced to make a life-or-death decision for one of his trial patients. Dr. Marcel is confronted by his past when a former acquaintance is brought into the ED.
Guest Stars:
Hannah James, Wendy Mateo, Lynne Lipton, Caitlan Taylor, Thomas H. Adisi
Dr. Marcel and Dr. Manning lay everything on the line to assist a sick woman. Dr. Halstead faces an uphill battle in getting participants involved in his clinical trial. Dr. Choi clashes with a patient who demands absolute perfection of himself.
Guest Stars:
Dr. Halstead finds continued success in his trial. Dr. Charles' daughter, Anna, receives life-changing news. Noah finds himself in a situation not even April can fix.
Guest Stars:
Roland Buck III, Obba Babatundé, Gary Alexander, Bonnie Bower, Anthony Irons
Dr. Choi helps a patient with chronic pain find a solution. Dr. Halstead considers a new path. Dr. Charles and Anna bond over a scary situation.
Guest Stars:
Charlie Bodin, Amy Rapp, Destini Huston, Kiera Prinz, Linda Reiter
Will runs into trouble when one of his trial patients falls ill. His own stress and symptoms have Ethan struggling to get through the day.
Guest Stars:
Jim Ortlieb, Nathan Hosner, Jerre Dye, Austin Tichenor, Kate Buddeke
Ethan hires an old Navy colleague to join him in the ED. A final custody hearing threatens to separate Charles and his daughter. Maggie must make a choice that will change Auggie's life.
Guest Stars:
Steven Weber, Christopher Farrar, Jill Abramovitz, Eric Epps, Ericka Ratcliff
As Maggie deals with her own trauma, she steps in to help a mother in need. Dean continues to stir the pot with more than one doctor. A patient comes to Med needing immediate treatment, but doesn't want it from them.
Guest Stars:
Steven Weber, Sola Thompson, Rene L. Moreno, Monica Orozco, Daniel Patrick Sullivan
Crockett deals with a patient who ends up having more in common with him than he thinks. Will and Ethan clash over a pregnant patient with an irregular heartbeat.
Guest Stars:
Barzin Akhavan, Wesley Truman Daniel, Lindsay Musil, Arash DeMaxi, Kate Romond
Ethan teams up with an unexpected person to treat a famous tennis player who is afraid his career might be over. Goodwin's new protocols cause a stir.
Guest Stars:
James Eckhouse, Hampton Fluker, Vincent Jamal Hooper, Monica West, Rita Simon
Dean and Ethan respond to a scene that brings back some bad memories. When Carol's condition worsens, Natalie is willing to do whatever it takes to get her mom feeling better.
Guest Stars:
Steven Weber, Joe Miñoso, Hanako Greensmith, Kumiko Konishi, Justin Rain
An auto accident sends Goodwin into a spiral as she tries to help a young boy and his mother. Natalie's secretive behavior begins to draw the attention of Dr. Marcel and Dr. Halstead.
Guest Stars:
Steven Weber, Gregory Alan Williams, Jessica Eleanor Grant, Daniel Cooney, Alys Dickerson
Third-year med students begin their rotation in the ED and Maggie keeps a careful eye on one of them. Natalie, whose mom's health takes another decline, tries to cover up how she broke the rules to treat her.
Guest Stars:
Steven Weber, Veronica Mejia, Edgar Miguel Sanchez, Mike Jimerson, Geoff Dow
Crockett worries he made a surgical error when a recent transplant patient comes in with complications. Carol is once again in distress. Will and Natalie must take action to right their wrong.
Guest Stars:
Steven Weber, Cordelia Dewdney, Jaq Seifert, Nicole Boucher, Kelly Anne Clark
Carol receives a second chance at life when a new heart becomes available. Ethan and Dean find themselves in hot water with an old patient. Will faces the consequences of the stolen trial medication.
Guest Stars:
Steven Weber, Ilya Baskin, Ato Essandoh, Tehmina Sunny, Margaret Colin
Burgess Jenkins, Bella Wholey Ortiz, Stephen Spencer, John Kelly, Gail Shapiro

22 Episodes