Brain enlists the aid of beavers to gain control over the flow of rivers.
Guest Stars:
Frank Welker
The mice make a series of comedy films and hit the big time.
Pinky and Brain have a new companion, Larry, but their newest plan just doesn't seem to pan out.
Guest Stars:
Billy West
In their latest plan, Pinky and Brain try to take over the steel mills in Pittsburgh, Pennsylvania by pretending to be a part of an endangered species called the Mousealopes.
Guest Stars:
Tress MacNeille, Frank Welker, John Mariano, Jeff Bennett
It's 1946 and Brain's new plan gets interrupted when he and Pinky encounter Billie and Snowball.
Brain gets caught up in winning a golf tournament, even though it interferes with his new plan.
Guest Stars:
Frank Welker
After the Earth gets the power of speech from his Silitronlinguifactor device, Brain comes up with a new plan.
Guest Stars:
Jeff Bennett, Earl Boen
Brain tries to get a package meant for him back from his neighbor.
Pinky becomes a guru during the 1960s.
Guest Stars:
Jess Harnell
It's Brain's birthday and Pinky plans a surprise party.
After getting a glimpse of his future, Brain abandons his attempts to take over the world and gets a job as a ski instructor.
Guest Stars:
Tress MacNeille, Jeff Bennett
The mice are looking to control tornados, but a pest keeps getting in their way.
Brain sings about past and present world leaders' failures.
Guest Stars:
Jeff Bennett
The mice need to get into a mine, but have to pretend to join a Amish-type society.
Brain's latest plan is a conspiracy theory about why he is not ruling the world.
Guest Stars:
Frank Welker, Jeff Bennett
Brain becomes a tap dancer with steam-powered legs in order to spread a subliminal morse code at the World's Fair.
Guest Stars:
Gail Matthius, John Astin, Dorian Harewood
Brain is out of ideas for taking over the world, so he tries to get some from writers.
Farmer Brain tries to grow an army of monster vegetables.
Guest Stars:
Frank Welker, Lauren Tom
Brain creates a cloning machine and plans to clone himself in order to create the best Celtic dance troupe the world has ever seen.
Guest Stars:
Laraine Newman, Jeff Bennett
Brain plans to use the Personalitron to give him irresistible charisma, but it winds up going to Pinky.
The mice learn of a secret organization, T.H.E.Y. (comprised of world leaders), and try to get in.
A house needed for Brain's latest plot becomes the set of a reality series about the people living there. So the mice become participants to get in.
Guest Stars:
Scott Valentine
To save his Las Vegas casino, Brain works as a lounge singer.
Guest Stars:
Jess Harnell, Tress MacNeille
Mr. Itch offers Brain control of the world in exchange for his soul, but Brain refuses. In a shocking twist, Pinky sells his soul to make it happen and Brain soon decides to get his friend back.
Guest Stars:
Tress MacNeille
Brain assumes the identity of Briany Jack, a hippie leader, and tries to create a peace chain to send a subliminal message.
Guest Stars:
Jeff Bennett
Brain's attempt to control Emperor Franz Josef get side tracked when he talks about his problems with psychiatrist Dr. Sigmund Freud.
Guest Stars:
Clyde Kusatsu
Brain enters the world of a sumo wrestling to acquire a paralyzing fish.
Brain takes control of a satellite to air his infomercial around the world, but the satellite belongs to the military and they want to capture whoever hacked into their systems.
Guest Stars:
Corey Burton, Frank Welker
Brain takes control over aquatic mammals for his latest plan and Pinky falls for a female sea lion.
Guest Stars:
Tress MacNeille, Jennifer Hale
Brain tries to change the Earth's weather patterns.
Guest Stars:
John Moschitta Jr.
A well-meaning tailor makes Pinky and Brain's lives miserable.
Guest Stars:
Gabrielle Carteris, Laraine Newman, Pat Musick
At a sleep away camp for world leaders' children, Brain tries to trick the children into placing listening devices in their parents' offices.
Guest Stars:
Gabrielle Carteris, Laraine Newman
To release Brain's leather repellant, the mice become baseball players.
Guest Stars:
Corey Burton, Frank Welker
Brain's latest plan for world domination is the Schpiel-Borg 2000, which hosts a retrospective of past episodes.
Pinky and Brain stage their own seperate musicals, which have varying degrees of success.
Spoofing Winnie the Pooh, Brainie and Pinklet try to steal honey from a bee hive.
Guest Stars:
John Rhys-Davies
Brain tries to create chaos in Hamlet's family and take over.
Brain tries to become a national hero by taking down a tobacco company.
Guest Stars:
Tress MacNeille
Taking the night off from trying to take over the world, Pinky and Brain try other things.
Guest Stars:
Julie Brown, Candi Milo, Michael Donovan
Brain tries to get surfers to put on his suntan lotion, Brain de Soleil, which creates a hypnotic effect.
Guest Stars:
Julie Brown
Brain enters Pinky's family in a contest to win $25,000.
Guest Stars:
Gail Matthius, Tress MacNeille, Frank Welker, Jeff Bennett, Eric Idle
Pinky has his own plan for world domination and Brain goes along with it.
Guest Stars:
John Glover
Brain explains why he should be leader in a mock educational film.
As network executives keep repeatedly changing their show, Pinky and Brain decide to quit.
Guest Stars:
Pat Musick, Dick Clark, Philip Maurice Hayes
As he prepares his plan for world domination, Brain goes to work teaching rebellious students.
Guest Stars:
Tress MacNeille
Pinky and Brain masquerade as a mother and child star respectively to get money needed for the next plan.
Guest Stars:
Tress MacNeille, Jeff Bennett
It's another usual night where Brain plans to take over the world, only it's seen from Pinky's point of view.